The risk of cardiovascular disease is elevated among both men and women with T2D, however, the risk has declined among men over recent years while it remains stationary in women.
Reasons for these sex differences remain unclear, and guidelines for diabetes treatment do not differentiate between sexes.
Accepted for publication 4 June 2014 Published 16 September 2014 Volume 2014:7 Pages 409—420 DOI https://doi.org/10.2147/DMSO.
S51301 Checked for plagiarism Yes Review by Single-blind Peer reviewer comments 2 Department of Endocrinology, Metabolism and Diabetes, Stockholm, Sweden Background: Women with type 2 diabetes (T2D) are less likely to reach the goals for hemoglobin A1c compared with men, and have higher all-cause mortality.
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Methods: Systematic searches were performed on Pub Med using “sex”, “gender”, and various glucose-lowering therapies as keywords.
Earlier reviews are summarized and results from individual studies are reported.